| |
|
| |
| |
| GENERIC
TECHNOLOGY STÚLB™ |
|
 |
MultiCoats
uses
STÚLB™
- laser based generic and unique
technology for deposition of thin and
ultra-thin films, nanocoatings and nanostructures.
The agent deposited might be of (in)organic
(including polymers, biopolymers, proteins)
or complex materials on (in)organic
or complex substrates in one device
and within one technological cycle.
The
physical-chemical properties might be
preliminary determinate. The technology
provide means for strong and permanent
control on the process.
Based on that, MultiCoats'
Labs and Divisions,
in collaboration and cooperation with
affiliate partners have developed several
families of thechnology methods for
coating and depositing wide range of
materials.. |
|
|
|
| |
|
| |
|
|
|
| DLC
Thin & Ultra thin Films
Tec |
|
|
Main
Lab deposited DLC thin films on several
different type of substrates, such as - SS-316 LMV,
Teflon, ceramics, semiconductor materials for infrared
optics (Si, GaAs, Ge, ZnSe as well.).
Cardiovascular Implants (stents) made of SS-316 and
NiTiNol have been coated by Ultra thin film ta-DLC
type.
There are two, completely different types of DLC films:
a-C and ta-C. The materials differ
in the index of refraction. Important distinction between
them is whether they were condensed from energetic ions
or from neutral carbon atoms. The most convenient means
of recognition is whether the imaginary part of the
index of refraction ni - 0,3 or
ni - 0,7 respectively.
Presented DLC films have index of refraction ni
within the range 1,3 - 2,4.
|
|
|
|
SS
316 |
Nitinol |
|
|
Teflon |
Raman |
|
|
| |
|
|
|
| Metal
Alloy M - 014 Ultra thin films Tec |
|
|
Nano
Lab. Biocompatible & biodegradable
metal alloy M-014 has been deposited as ultra thin
film on polymeric, metal and ceramic substrates.
The alloy has fixed and sustainable rate of degradation
implanted in tissue or within blood stream, wich makes
it aplicable for drug(s) eluting matrixes..
Suitable for usage in Drug Delivery Systems as carriage
- micro balls or rods or ultra thin film degradable
cover of drug(s) container(s).
|
|
|
|
| |
|
|
|
| Metal
nano particles incorporated within DLC matrix Tec [ MDLC
Stent ] |
|
|
Nano
Lab. Metal
nanoparticles of Silver and Platinum are incorporated
within DLC matrix coatings. The next step is to incorporate
nanoparticles of Titanium and Zirconium within DLC
matrix. Some Researchers as US NRL published info
that "...DLC-silver and DLC-platinum composite
films reveals ... self-assemble into particulate nano
composite structures that possess a high fraction
of sp3-hybridized carbon atoms. DLC-silver-platinum
films demonstrated exceptional antimicrobial properties
against Staphylococcus and Pseudomonas aeruginosa
bacteria."
Nanostructures
with highly controllable properties integrated whithin
inorganic biocompatibles, polymers, biopolymers and
biological system at nanoscale. might be used for
applications in new hybrid nano devices with unique
properties, . STÚLB™
is capable of forming hybrid nanostructures and biofilms
in single technology cycle.
|
|
|
|
| |
|
|
|
| DLC
Coatings on polimeric goffered Textile
Substrate Tec |
|
|
MultiCoats.
BioCoat
Lab Division started deposition
of nano films of DLC and/or gelatine and/or gelatine-drug-charged
on goffer textile substrate, to be used as cardiovascular
implant. Ultra Hydrophobic biocompatible hybrid material
might be coated as well. The actual state of the textile
surfsce is shown at microscopic photo picture to the
left.
Normaly, the textile not treated by gelatine has water-permeability.of
about 0.8 - 1.5 l/min/sq.cm and practicly zero after
treatment.
|
|
|
|
| |
| |
| Organic
Coatings : Polymer Sensors, BioSensors |
|
| |
|
|
|
| Polymer
P-312 Coatings
Tec |
|
|
MultiCoats.
Ppreparing
some target samples for deposition of thin and ultra
thin films of polymer P 312 (our designation), besides
known properties, such as biocompatibility and biodegradability
a photoluminiscence has been observed within "blue"
part of the spectrum with responce time fare beyond
10 ns.
These biodegradable polyphosphoesters are appealing
for biological and pharmaceutical applications because
of their biocompatibility and similarity to bio-macromolecules
such as nucleic acids.
P-312 has potential and properties to become gradient
of Drug Delivery Systems.
|
|
|
|
| |
|
|
|
| Polymer
D-712 Coatings
Tec [Heavy metals Sensor device] |
|
|
MultiCoats'
Division
unit has started testing ultra thin polymeric films
for heavy metal detection sensor device.
The Polymer D 712 (our designation
name) and some of it's generations have shown
properties usable for highly sensitive sensor made
in form of Thin and Ultra Thin films..
Loooking for cooperation and partnership within FP7
of EU.
|
|
|
|
| |
|
|
|
| Polymer
P-329 Coatings
Tec |
|
|
MultiCoats'
division
BioCoat Lab has
started depositions of biocompatible and biodegradable
nano coats, based on P-329 polymer and its co-polymers,
on DLC coated cardiovascular Stent, The polymer is
to be charged by one or more drugs as drug carrier
on as drug's cover-up thin film within drug(s) eluting
matrix.
P-329 nano films might be coated (sandwich) by ultra
thin layer of biodegradable and biocompatible metal
alloy M-014 as mechanical protector,
|
|
|
|
| |
|
|
|
| PGLA
(RG 503 H Poly-glyco-lactic-acid)
thin film deposition
Tec |
|
|
MultiCoats'
division
Main Lab using
STÚLB™
laser technology performed controllable deposition
of complex biopolymers and organic materials. Deposition
on PGLA rezomer – synthetic biodegradable and biocompatible
biopolymer in nano coats has been done and tested.
Material is applied in pharmaceutics and stent manufacturing.
Multi-layered films are deposited without any risk
of harming deposited material properties onto any
surface. The technology does not use any dissolving
agent in any aggregate condition. Biopolymer bone
structure analysis of these films have been quantified
using Fourier Transform Infrared Spectroscopy (FTIR)
for comparisons to native materials.
|
|
|
|
|
SEM |
Native |
|
nano
film FTIR |
|
|
| |
|
|
|
| Polymer
P-329 Coatings
Tec |
|
|
MultiCoats'
division
BioCoat Lab has
done controllable deposition of complex biopolymeric
material known as Mioglobin B - synthetic biodegradable
biopolymer, protein with mol. w. 17400 Dalton. The
material is used in pharmaceutics and cardiovascular
stenting. Multi-layered films are coated without risk
of damaging agent's properties onto many substrates.
The tec does not apply dissolvents and the target
migt be in any aggregate condition. Myoglobin B thin
films have been subject to structural analysis and
quantified using Fourier Transform Infrared Spectroscopy
(FTIR) for comparisons to native materials.
|
|
|
|
| |
| |
|
|
| |
| |
| |
| |
| |
| |
| |
| |
| |
|
| |
| |
| |
)
)
)
)
)
)
)
)
)
)
)
)
)
)
)
)
